Program

The program of the event will have relevant and current issues in the area of therapeutic drug monitoring and clinical toxicology, promoting discussions within the theme: "Therapeutic Monitoring of Drugs and Clinical Toxicology for a Globalized World." The activities will be mediated and presented by Brazilian and international scientists and professionals, who are actively involved in this theme, with a view to improving patient care in a wide range of economic and social settings. 

 

PROGRAM DOWNLOAD

Preliminary Program
 
22/09/2019 - Sunday
18:00 - 19:30
Room 1 - SONATA 3
Welcome address: Rafael Linden, 2019 Congress Organizing Committee
Presidential Welcome address: Teun van Gelder, President, IATDMCT

Plenary presentation: Therapeutic Drug Monitoring and Clinical Toxicology for a Globalized World
(Pierre Wallemacq, Belgium)

IATDMCT awards: Loralie Langman, Past-President, IATDMCT
19:30 - 21:00
Welcome reception
20:30 - 23:00
Young scientists night out
 
23/09/2019 - Monday
07:45 - 08:40
Room 1 - SONATA 3
Morning session Anti-infective
Clinical use of PK/PD for individualization of antibiotic therapy
at the ICU (Birgit Koch, The Netherlands)

Chairs: Simone Verza and Mariele Charao
Room 2 - MODERATO
Morning session
Pharmacogenetic of tamoxifen


Prospective Studies of Tamoxifen Pharmacogenetics and Metabolism: what have we learned (Jesse Swen, The Netherlands)

PGx of tamoxifen: metastatic advanced patients in Japanese population (Yusuke Tanigawara, Japan)

Chair: Marina Venzon Antunes
08:45 - 10:30
Room 1 - SONATA 3
Symposium TDM in oncology
Exposure-response relationships of commonly used Mabs


TDM of biologics in oncology- what can we learn from biologics used in inflammatory disease and how to apply in oncology?
(Annick de Vries, The Netherlands)

Exposure-response relationships of commonly used Mab
(Fabienne Thomas-Jean, France)

Chairs: Gareth Veal and Vikram Suryaprakash Gota
Room 2 - MODERATO
Symposium Immunosuppressive Drugs TDM of Immunosuppressive Drugs-personalized therapy

Tacrolimus intracellular concentrations: improving patient and graft care
(Florian Lemaitre, France)

Update of immunosuppressive drugs TDM in pediatric population (Tomoyuki Mizuno, USA)

Insight anti-infective drugs in transplant recipients
(Andrea Diniz, Brazil)

Chairs: Teun Van Gelder and Pierre Wallemacq
Room 3 - CANTATA
Symposium Biologicals
Proactive therapeutic drug monitoring of biologics in inflammatory bowel diseases: induction treatment and cost


Induction anti-TNF concentrations and primary nonresponse in adult IBD patients
(Niels Vande Casteele, USA)

Is there a place for therapeutic drug monitoring of drugs other than infliximab for inducing response in patients with inflammatory bowel diseases?
(Erwin Dreesen, Belgium)

Financial implications of anti-TNF therapeutic drug monitoring
(Murray Barclay, New Zealand)

Chairs: Núria Padullés and Andresa Heemann Betti
10:30 - 11:00
Coffee break at the exposition area
11:00 - 12:15
Room 1 - SONATA 3
Plenary session
Irving Sunshine Award Winner
Patsalos Award Winner

Chair: Loralie Langman
12:15 - 13:30
Room 1 - SONATA 3
Industry workshop - Symposium Waters
Mass Spectrometry Toxicology Screening Approaches and a Case Study in Brazil.
Michelle Wood (Waters, UK) and José Luiz da Costa (Unicamp, Brazil)

EXPOSITION AREA
Poster presentation
13:30 - 14:45
Oral Presentations - Rooms 1, 2, 3 Click here

Room 1 - SONATA 3
Oral presentations Clinical Toxicology
Chairs: Mariele Charão and Cristiane Bastos de Mattos

Room 2 - MODERATO
Oral presentations Anti-infective drugs
Chairs: Magda Perassolo and Ana Luiza Ziulkoski

Room 3 - CANTATA
Oral presentations Pharmacogenetic/Oncology
Chairs: Marina Antunes and Renato Minozzo
14:45 - 15:15
Coffee break at the exposition area
15:15 - 17:00
Room 1 - SONATA 3
Symposium Young scientists

Alternative sampling strategies to support therapeutic drug monitoring of anti-TB drugs in TB endemic areas.
(Samiksha Ghimire, The Netherlands)

Study design and reporting matters: why IATDMCT members work was not included in important Systematic Reviews of TDM
(Jana Stojanova, Chile)

Challenges and opportunities for model-informed precision dosing in very young children (Tomoyuki Mizuno, USA)

Chairs: Markus R. Meyer and Brenda de Winter
Room 2 - MODERATO
Symposium: Therapeutic Drug Monitoring in developing countries

Therapeutic monitoring of immunosuppressive drugs
(Renato Foresto, Brazil)

How can we bridge the gap between developed and developing countries in TDM?
(Paula Schaiquevich, Argentina)

Improving the old and in with the new: the expanding role of TDM in the management of Mycobacterium tuberculosis
(Andres Felipe Zuluaga, Colombia)

Chair: Rafael Linden
Room 3 - CANTATA
Symposium Anti-infective agents and therapeutic drug monitoring: the ultimate precision medicine when no two patients are alike

The role of the laboratory in achieving personalised anti-infective TDM
(Danijela Kocic, Australia)

Renal replacement therapy and antimicrobial therapy: a knowledge vacuum
(Jan-Willem Alffenaar, The Netherlands)

Therapeutic drug monitoring and safety of voriconazole therapy in patients with hepatic disease (Miao Yan, China)

Chairs: Debbie Marriott and Natalia Brucker
17:00 - 18:00
Room 1 - SONATA 3
Businesses meetings of scientific committees

Committee 1: Immunosupressive Drugs
Committee 2: Pharmacometrics
Committee 3: Clinical Toxicology
Room 2 - MODERATO
Businesses meetings of scientific committees

Committee 1: Young Scientists
Committee 2: Pharmacogenetics
Committee 3: Alternative Samplings Strategies
Room 3 - CANTATA
Businesses meetings of scientific committees

Committee 1: Anti Infective Drugs
Committee 2: TDM in Oncology
Committee 3: Toxicology and Enviromental Health
18:00 - 20:00
Room 1 - SONATA 3
Brazilian Cocktail
 
24/09/2019 - Tuesday
07:45 - 08:40
Room 1 - SONATA 3
Morning session
Alternative sampling strategies

Dried blood sampling techniques distinct from dried blood samples: what’s available and what’s the status?
(Christophe Stove, Belgium)

Chair: Mariele Charão
Room 2 - MODERATO
Morning session
Immunosuppressive Drugs

Biomarkers in transplantation
(Pierre Marquet, France)

Chair: Rafael Linden
08:45 - 10:30
Room 1 - SONATA 3
Symposium Anti infective
Not just tuberculosis: the therapeutic challenges of acid-fast organisms


Nocardia, the ultimate opportunist
(Debbie Marriott, Australia)

Mycobacterium abscessus: a rising pathogen (Michael Neely, USA)

Non-tuberculous mycobacteria: does TDM have a place?
(Jan-Willem Alffenaar, The Netherlands)

Chairs: Simone Verza and Miao Yan
Room 2 - MODERATO
Symposium
New psychotropic drugs


Techniques for Toxicokinetic Studies of NPS (Markus Meyer, Germany)

Epidemiology of NPS consumption by oral fluid analysis (Jose Luiz da Costa, Brazil)

Detection of NPS requires NPS (New Performant Strategies)
(Christophe Stove, Belgium)

Chairs: José Luiz da Costa and Vanessa Steenkamp
Room 3 - CANTATA
Symposium
Clinical use of precision dosing software


Current and Future Developments in Model-Informed Precision Dosing (Ron Keizer, USA)

Chances and challenges for implementation of precision dosing software from a pharmacometric perspective
(Sebastian Wicha, Germany)

Use of PBPK model simulator for the individualized therapy (Ikuko Yano, Japan)

Chairs: Paula Schaiquevich and Jean-Baptiste Woillard
10:30 - 11:00
Coffee break at the exposition area
11:00 - 12:15
Room 1 - SONATA 3
Plenary session
Advanced TDM of tacrolimus
(Pierre Marquet, France)

Chair: Teun Van Gelder
12:15 - 13:30
Room 1 - SONATA 3
Industry workshop - Symposium Shimadzu
Fully automated sample preparation procedure for TDM by liquid chromatography tandem mass spectrometry
(Marcos Albieri Pudenzi, Shimadzu)

EXPOSITION AREA
Poster presentation
14:30 - 18:00

Excursion to Iguassu Falls
(optional activity, not included in registration fee)

Social activity at the hotel
 
25/09/2019 - Wednesday
07:45 - 08:40
Room 1 - SONATA 3
Morning session
Clinical Toxicology


Immunotoxicity: drug-induced and herbal-induced hypersensitivity reactions (Manuela Neuman, Canada)

Oxidative Stress and Inflammation in Kidney Transplantation. The effect of immunosuppression (Eberhard Wieland, Germany)

Chair: Manuela Neuman
Room 2 - MODERATO
Morning session
Toxicology & Environmental Health


Metals/lead poisoning in the 21st century
Changing paradigms: serum vs whole blood lead concentrations
(Souleiman El Balkhi, France)

Lead: The human risk from drinking water
(David Kinniburgh, Canada)

Chair: Nicolas Venisse
08:45 - 10:30
Room 1 - SONATA 3
Symposium Pharmacogenetic
PGx in oncology


DPYD and 5-FU
(Teun van Gelder, The Netherlands)

UGT1A1 and beyond. Can a validated molecular signature be used to guide the prescription of irinotecan with associated therapies in advanced colorectal or pancreatic cancers?
(Jean Christophe Boyer, France)

Tyrosine Kinase Inhibitors and PGx of ABCG2 (Tomohiro Terada, Japan)

Chairs: Vicent Haufroid and Yusuke Tanigawara
Room 2 - MODERATO
Symposium Alternative sampling strategies
What’s new in microsampling


Adduct monitoring in blood microsamples (Lisa Delahaye, Belgium)

Drug monitoring via fingerprints
(Melanie Bailey, UK)

IATDMCT method validation guidelines for dried blood spot assays
(Jan-Willem Alffenaar, The Netherlands)

Chairs: Rafael Linden and Christophe Stove
Room 3 - CANTATA
Symposium
Contributed papers
Oral Presentations - Click here

Chairs: Natalia Brucker and Rafael Lanaro
10:30 - 11:00
Coffee break at the exposition area
11:00 - 12:15
Room 1 - SONATA 3
Plenary session
Pharmacology & Toxicology of New Psychoactive Substances
(Hans H. Maurer, Germany)

Chair: Pierre Wallemacq
12:15 - 13:30
Room 1 - SONATA 3
Industry workshop - Symposium Thermo Scientific
Performing Mass Spectrometry Based Analysis with Confidence : Robust, Reliable, Sensitive Assays for Toxicology
(Xiaolei Xie, Ph.D Manager - Clinical Research Vertical Market)

EXPOSITION AREA
Poster presentation
13:30 - 14:45
Oral Presentations - Rooms 1, 2, 3 Click here

Room 1 - SONATA 3
Oral presentations Alternative Sampling
Chairs: Birgit Koch and Simone Verza

Room 2 - MODERATO
Oral presentations Immunosuppressive
Chairs: Pierre Marquet and Cristiane Bastos de Mattos

Room 3 - CANTATA
Oral presentations Pharmacometrics
Chairs: Marina Antunes and Andresa Heemann Beti
14:45 - 15:15
Coffee break at the exposition area
15:15 - 17:00
Room 1 - SONATA 3
Symposium
Mass spectrometry in clinical and forensic toxicology


Qualitative and Quantitive Solutions in 24/7 Toxicological Analysis
(Markus Meyer, Germany)

High-resolution mass spectrometry for fentanyl analog screening, confirmation and discovery
(Michelle Wood,UK)

Ready to use Mass Spectrometry based Solutions for Toxicology (Diego Assis, Brazil)

Chairs: Eric J.f. Franssen and José Luiz da Costa
Room 2 - MODERATO
Symposium Toxicology & Environmental Health
Environmental pollutants and health outcomes: an overview of recent evidence


Bisphenols and metabolic diseases
(Nicolas Venisse, France)

Pesticide environmental exposure: molecular and biochemical biomarkers and morphometric parameters in pregnant women, placenta and newborn
(Gladis Magnarelli, Argentina)

Effects of a mixture of persistent organic pollutants on the thyroid function of a Belgian population
(Patrice Dufour, Belgium)

Chairs: David Kinniburgh and Mariele Charão
Room 3 - CANTATA
Symposium Pharmacometrics

R-shiny tools for pharmacometrics in drug development
(Patrick Nolain, France)

Development and applications of pharmacometric tools for routine clinical practices
(Jean Baptiste Woillard, France)

Implementing model-based dosing in clinical practice
(Birgit Koch, The Netherlands)

Chairs: Jean-Baptiste Woillard and Brenda de Winter
17:00 - 18:00
Room 1 - SONATA 3
IATDMCT AGM (Annual General Meeting)
 
26/09/2019 - Thursday
08:45 - 10:00
Room 1 - SONATA 3
Symposium
Contributed papers
Oral Presentations - Click here

Chairs: Rafael Linden and Magda Perassolo
Room 2 - MODERATO
Symposium Clinical Toxicology
Emergencies in Toxicology

Scorpion envenomation in South America
(Fábio Bucaretchi, Brazil)

Acute Intoxications: taking clinical decisions before laboratory results
(Eduardo Mello de Capitani, Brazil)

Analytical Strategy for Effective 24/7 ClinTox Services - From Screening to Simplified Blood Level Assessment
(Hans H. Maurer, Germany)

Chairs: Rafael Lanaro and Cristiana Stefan
10:00 - 10:30
Coffee break at the exposition area
10:30 - 11:15
Room 1 - SONATA 3
Plenary session
Breaking the devotion to breakpoints and P-values for anti-infectives
(Michael Neely, USA)

Chair: Marina Venzon Antunes
11:15 - 12:45
Closing ceremony
Gold Sponsor
Silver Sponsor
Bronze Sponsor
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Fellini Events

 

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Centro - 90010-080
Porto Alegre, Brazil

 

+55 (51) 3216-6300
contact@iatdmct2019.org

 

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